BD Peripheral Intravenous Catheters (PIVCs): Insyte vs Nexiva
Peripheral Intravenous Catheters (PIVCs) support the delivery of medications, fluids, and therapies across a wide range of clinical settings. However, not all PIVCs are designed the same way. In this guide, we explore the different types of BD™ peripheral IV catheters, including the BD Insyte™ and BD Nexiva™ families, to help you understand their features and determine which system may be best suited for different clinical needs.
What are the Different Types of BD Peripheral IV Catheters?
Peripheral IV catheters are commonly classified by their intended duration of therapy, including short peripheral IV catheters, extended dwell catheters, and midline catheters. Within the short PIVC category, manufacturers such as BD offer two different device designs, including straight (non-integrated) and integrated peripheral IV catheters, each suited to different clinical workflows:
- Straight PIVCs: Conventional (BD Insyte) or safety IV catheters (BD Insyte Autoguard), available winged or non-winged. Ideal for quick insertion in ERs or outpatient settings.
- Integrated PIVCs: All-in-one systems (BD Nexiva) with extension sets and stabilization platforms. Reduce movement and dislodgement (affects 20% of IVs) and streamline workflows.

How to Choose the Right PIVC
Choosing the right peripheral IV catheter involves balancing patient factors, clinician technique, and device design.1 When selecting a PIVC, clinicians should consider expected dwell time, vein condition, insertion environment, and risk of complications such as infiltration or phlebitis. The following considerations can help guide peripheral intravenous catheter selection based on patient needs, treatment requirements, and the clinical environment.
Patient vascular access needs
- Vein condition and difficult vascular access: Patients with fragile, small, or difficult-to-access veins may benefit from catheter technologies designed to improve first-attempt success and minimize repeated insertion attempts.
- Patient mobility and catheter stabilization: Active or ambulatory patients may be more prone to catheter movement. Integrated systems can help improve catheter stabilization, which can reduce the risk of accidental dislodgement and IV catheter complications.1
Long-term catheter performance
- Expected dwell time: Longer anticipated therapy may make integrated catheter systems and advanced catheter materials more advantageous due to the increased importance of stabilization to support ongoing treatment.
- Catheter durability: Longer-term peripheral therapy increases the importance of catheter stability, securement, and material performance to help maintain reliable vascular access throughout treatment.2
Clinical environment
- Emergency versus planned care: When rapid peripheral vascular access is the priority, straight catheter systems are often preferred because of their familiar, streamlined design.
- Blood exposure and infection prevention: In environments where blood exposure is a concern, devices with blood control technology and passive safety features can help reduce exposure during insertion, while lowering the risk of needlestick injuries.
Regardless of the peripheral intravenous catheter design selected, safety-engineered features such as blood control technology, passive shielding, and advanced catheter materials can significantly reduce needlestick injuries, improve first-attempt success rates, and support safer peripheral IV therapy.
How BD PIVC Technologies Improve Performance
Both the BD Insyte™ and BD Nexiva™ families incorporate technologies designed to improve IV catheter insertion success, safety, and patient outcomes. While individual models offer different combinations of features, these innovations help distinguish conventional, safety-engineered, and integrated PIVC options across the BD portfolio.
- BD Instaflash™ Needle Technology: The notched needle provides visual confirmation of vessel entry to support first-attempt insertion success. First-attempt success reached 98.72%, compared with 88.87% for the control catheter.3
- BD Vialon™ Catheter Material: This biomaterial softens up to 70% within the vein. Vialon™ catheters achieve longer dwell times and 50% lower phlebitis rates compared with Teflon catheters.4
- Blood Control Technology: Helps limit blood leakage during catheter insertion by containing blood for up to 10 seconds. This technology reduces blood leakage by approximately 95% compared with conventional catheters.5
- Safety Mechanisms: Safety-engineered catheter systems incorporate needle protection features designed to reduce needlestick risks. The BD Nexiva™ Catheter System was associated with a 93% reduction in needlestick injuries following implementation in one hospital setting.6

Rather than representing separate technologies, the BD Insyte™ and BD Nexiva™ portfolios build progressively on one another. As additional safety and blood control features are incorporated, the peripheral intravenous catheters evolve from conventional designs to fully integrated systems with enhanced stabilization and workflow benefits. The illustration below highlights the structural differences between conventional straight IV catheters and integrated systems.

Supporting Safer and More Effective IV Therapy
Selecting the appropriate peripheral intravenous catheter requires consideration of the patient’s vascular access needs, expected therapy duration, and clinical environment. Within the BD portfolio, straight catheter systems such as the BD Insyte™ family may be suitable when rapid access and simplicity are priorities, while integrated systems such as BD Nexiva™ can provide additional stabilization, blood control, and safety features for more complex care situations.
Advances in PIVC technology, including visualization features, advanced catheter materials, blood control, and safety mechanisms, are designed to support successful insertion, reduce complications, and improve clinician safety. BD vascular access technologies have been evaluated across multiple clinical studies,7 with research supporting improvements in first-attempt success, blood leakage reduction, catheter performance, and needlestick prevention.
Regardless of catheter design, proper insertion technique, securement, and ongoing monitoring remain essential for successful IV therapy. Peripheral IV catheters should be monitored daily for signs of complications,1 including infiltration, phlebitis, infection, or dislodgement, and removed when no longer clinically necessary.
FAQs
A straight peripheral IV catheter (PIVC) is a traditional catheter design that is inserted directly into the vein and typically requires separate components for extension and stabilization. Integrated PIVC systems combine the catheter with features such as extension tubing, stabilization platforms, and safety mechanisms in one device. These systems may help reduce catheter manipulation, improve stabilization, and support workflow efficiency in certain clinical settings.
First-attempt insertion success helps reduce the need for repeated insertion attempts, which can improve patient comfort, reduce delays in treatment, and support more efficient clinical care. Technologies designed to improve visualization and insertion confidence, such as BD Instaflash™ Needle Technology, can help clinicians achieve successful vascular access on the first attempt.
Some facilities flush PIVCs before and after medication administration, while intermittent-use catheters may be flushed at scheduled intervals according to local guidelines to maintain patency. The frequency of PIVC flushing depends on institutional protocols, catheter type, medication administration requirements, and patient-specific considerations. Flushing should always follow established clinical protocols, including recommended flush solution, volume, and technique.
Safety-engineered IV catheters incorporate features such as passive or active needle shielding and blood control mechanisms to help reduce clinician exposure to blood and prevent needlestick injuries. These features are designed to improve safety during catheter insertion and handling while supporting safer vascular access practices.
Peripheral IV catheters are monitored through regular assessment of the insertion site, catheter function, and patient symptoms throughout treatment. Healthcare providers typically check for signs of complications such as swelling, redness, pain, leakage, warmth, infiltration, phlebitis, infection, or catheter dislodgement. The catheter should also be assessed before use to confirm patency and proper function. Ongoing monitoring helps identify complications early, and PIVCs should be removed when they are no longer clinically necessary.
References
- Zingg W, Barton A, Bitmead J, et al. Best practice in the use of peripheral venous catheters: A scoping review and expert consensus. Infect Prev Pract. 2023;5:100271. doi: 10.1016/j.infpip.2023.100271.
- Kleidon T. Paths to Precision: Device Decisions — Ten Tips to Tackle Vascular Access Device Selection. ICU Medical Human Connections. 2025 Feb 25. Available from: https://www.icumed.com/about-us/clinical-connections/vascular-access/paths-to-precision-device-decisions/
- Seetharam AM, Raju U, Suresh K. A randomized controlled study to compare first stick success with Instaflash technology: The FIRSST study. J Vasc Access. 2022;25(1):203–209. doi: 10.1177/11297298221080369.
- Kuş B, Büyükyılmaz F. Effectiveness of Vialon biomaterial versus Teflon catheters for peripheral intravenous placement: A randomized clinical trial. Jpn J Nurs Sci. 2020;17:e12328. doi: 10.1111/jjns.12328.
- Onia R, Eshun-Wilson I, Arce C, et al. Evaluation of a new safety peripheral IV catheter designed to reduce mucocutaneous blood exposure. Curr Med Res Opin. 2011;27(7):1339–1346. doi: 10.1185/03007995.2011.581275.
- Easterlow D, Hoddinott P, Harrison S. Implementing and standardising the use of peripheral vascular access devices. J Clin Nurs. 2010;19(5–6):721–727. doi: 10.1111/j.1365-2702.2009.03098.x.
- BD. Clinical Evidence Compendium. BD. March 2025. Available from: https://www.bd.com/content/dam/bd-assets/bd-com/emea-assets/en-no/images/solutions/vascular-access-management/fy26_bd163576_pivc_ clinical_compendium_nordics.pdf